|
KMID : 0381319860250010001
|
|
Korean Journal of Occupational Health
1986 Volume.25 No. 1 p.1 ~ p.8
|
|
|
A study on hemoglobin, blood lead and zinc protoporphyrin levels in lead smelter workers
|
|
김정만/Kim, Jung-Man
김형아/이광묵/이은영/강재복/Kim, Hyoung-Ah/Lee, Kwang-Mook/Lee, Eun-Young/Kang, Jae-Bok
|
|
|
Abstract
|
|
|
For the purpose of obtaining cn effective biological monitoring data, study to evaluate the health consequences of lead absorption was conducted using lead smelter workers who have been exposed to lead occupationally.
The study population was the 90 lead-exposed workers and 115 non-exposed workers who were working in the lead smelting.
The biological parameters chosen for this study were as follows; blood lead(PbB), hemoglobin (Hb), zinc protoporphyrin in whole blood (ZPP), urine lead (PbU), coproporphyrin in urine (CPU), δ-aminolevulinic acid in urine (ALAU), δ-aminolevulinic acid dehydratase acitivity in whole blood (ALAD).
The results obtained were as follows;
1. The average work duration were 138.3±63.2 months and 131.1±62.9 months in lead exposed smelter workers and non-lead smelter workers, respectively. In lead-exposed smelter workers and non-lead smelter workers, the average age were 39.0±7.8 years and 38.1±7.8 years, respectively.
2. The mean value of blood lead level were 48.3±12.4㎍/100㎖ and 35.6±6.4㎍/100㎖ in lead-exposed smelter workers and non-lead worders, respectively.
3. The mean value of zinc protoporphyrin were 64.3±28.2㎍/100㎖ and 35.6±6.4㎍/100㎖ in lead-exposed smelter workers and non-lead worders, respectively.
4. The mean value of hemoglobin were 14.27±0.67㎍/100㎖ and 14.95±0.29㎍/100㎖ in lead-exposed smelter workers and non-lead workers, respectively.
5. There was very significant correlation between PbB and ZPP(r=0.8668). While there was significant increase of correlation coefficient between PbB and log transformation value of ZPP(r=0.9025).
6. There was statistically significant correlation between PbB and Hb(r=-0.732).
7. There was statistically significant correlation between ZPP and Hb(r=-0.687).
8. The only significant difference between workers with longer and those with shorter duration of lead exposure was found in ZPP levels; the other differences did not reach the level of statistical significance.
9. With above results measurement of ZPP could be recommended as one of good reliable screening test method to replace the very difficult measurement of PbB in industrial setting.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|